Denso 221-0509 Radiator
OE Quality 60-Day Returns
Denso

Denso 221-0509 Radiator

Brand Denso 221-0509
Core Height 17.7500
Core Thickness 1.0000
Core Width 29.0620
Inlet Diameter 1.3750
Outlet Diameter 1.3750
Transmission Oil Cooler Included YES
Fits Toyota · 7 vehicles

OE experience. Built to OE standards for reliable fit and performance.

Durability tested. Passes strict function and durability checks.

Transmission oil cooler included. Integrated cooling support in one radiator assembly.

Cross-references APDI 8012453, CSF 2822 and DPI Performance Racing Products 2453 for the same application. See all 11.

$170.64Free shipping
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Denso 221-0509 Radiator for Highlander

Denso 221-0509 is an OE-style radiator built for consistent engine cooling and dependable fitment. It is made for 2001-2007 Toyota Highlander applications and includes an integrated transmission oil cooler for vehicles that route automatic transmission fluid through the radiator.

Key Features

  • Fits 2001-2007 Toyota Highlander
  • Radiator core dimensions: 17.7500 in. height, 29.0620 in. width, 1.0000 in. thickness
  • Inlet and outlet diameters: 1.3750 in.
  • Transmission oil cooler included
  • OE-based configuration for fitment and cooling performance
  • Part number 221-0509

Detailed Description

This Denso radiator is engineered around OE specifications for the Toyota Highlander, with core size, tank layout, fin pitch, and materials selected to match factory requirements. Denso supplies radiators to vehicle manufacturers worldwide, and that OE experience is reflected in the design and testing of this replacement radiator. For drivers searching for a Toyota Highlander radiator, Denso 221-0509 offers the correct dimensions and cooling-system layout for 2001-2007 models.

This part cross-references APDI 8012453 and Spectra Premium CU2453 for the same application.

What It Helps Address

  • Engine overheating caused by a leaking or restricted radiator
  • Coolant loss from cracked tanks or damaged core passages
  • Transmission temperature concerns when the factory cooler is part of the radiator
  • Poor heat transfer from an aging Toyota Highlander radiator
  • Fitment issues from using a non-OE-style replacement

Installation Notes and Tips

Verify inlet and outlet hose sizes before installation and confirm the transmission cooler line connections match the vehicle setup. Flush the cooling system, inspect hoses and clamps, and replace worn coolant components as needed to help protect the new radiator. Confirm fitment against the vehicle’s year and cooling configuration before final assembly.

Quality Assurance

Denso radiators are built to OE standards and undergo durability and function testing before release. That testing process supports reliable cooling performance and consistent fitment for the Toyota Highlander application covered by part number 221-0509.

Related reading

This part fits 7 vehicles
Always verify fitment with your vehicle's VIN if unsure. Submodel & trim restrictions may apply.
YearMakeModelPositionNotes
2007ToyotaHighlanderN/A—
2006ToyotaHighlanderN/A—
2005ToyotaHighlanderN/A—
2004ToyotaHighlanderN/A—
2003ToyotaHighlanderN/A—
2002ToyotaHighlanderN/A—
2001ToyotaHighlanderN/A—
Directly replaces or cross-references 11 part numbers
Cross-reference numbers are provided for identification purposes only. Always confirm fitment before ordering.
APDI — 8012453CSF — 2822DPI Performance Racing Products — 2453OSC — 2453Reach Cooling — 41-2453Spectra Premium — CU2453Toyota — 16400-28240Toyota — 16400-28260Toyota — 16410-YZZAKTYC Cooling - Archived — 2453Vista Pro — 432693