Denso 221-0518 Radiator

Brand Denso 221-0518
Core Height 23.6250
Core Thickness 1.2500
Core Width 27.1870
Inlet Diameter 1.5620
Outlet Diameter 1.5620
Transmission Oil Cooler Included YES
Fits Toyota · 10 vehicles

OE experience. Built to meet strict OE standards for fit, performance, and reliability.

Radiator performance. Helps maintain proper engine cooling and function.

Transmission oil cooler included. Adds integrated cooling support in one radiator assembly.

Cross-references APDI 8012376, CSF 3238 and DPI Performance Racing Products 2376 for the same application. See all 12.

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Denso 221-0518 Radiator for Toyota Sequoia and Tundra

The Denso 221-0518 radiator is built for direct-fit cooling performance in select Toyota truck and SUV applications. It uses OE-style dimensions and materials to support proper engine temperature control, with an integrated transmission oil cooler included for vehicles that require it.

Key Features

  • Core height: 23.6250 in.
  • Core width: 27.1870 in.
  • Core thickness: 1.2500 in.
  • Inlet diameter: 1.5620 in.
  • Outlet diameter: 1.5620 in.
  • Transmission oil cooler included: Yes
  • OE-based radiator configuration for fitment consistency

Detailed Description

Denso Part Number 221-0518 is a radiator engineered for 2001-2007 Toyota Sequoia and 2004-2006 Toyota Tundra applications. Denso supplies radiators to original equipment vehicle manufacturers worldwide, and this radiator reflects that OE-focused experience through its configuration, tank design, fin pitch, core dimensions, and material selection. The result is a radiator built to match factory-style fitment and cooling requirements for the Toyota Sequoia and Toyota Tundra platform.

This radiator is sized with a 23.6250-inch core height, 27.1870-inch core width, and 1.2500-inch core thickness, along with 1.5620-inch inlet and outlet diameters. Those dimensions matter for maintaining proper coolant flow and heat exchange in demanding driving conditions, especially when the engine and transmission are working under load. Denso 221-0518 is a practical replacement choice when the original radiator is leaking, restricted, or no longer maintaining stable operating temperatures.

This part cross-references APDI 8012376 and Spectra Premium CU2376 for the same application.

What It Helps Solve

  • Engine overheating caused by a failing radiator core
  • Coolant leaks from cracked tanks or worn radiator seams
  • Transmission temperature concerns when the cooler circuit is part of the system
  • Reduced cooling efficiency from clogged or damaged internal passages
  • Fitment issues from using a radiator that does not match OE dimensions

Installation Notes and Tips

Fits 2001-2007 Toyota Sequoia, N/A. Fits 2004-2006 Toyota Tundra, N/A. Verify inlet and outlet sizing, mounting points, and transmission cooler line routing before installation. Flush the cooling system, inspect hoses and clamps, and refill with the correct coolant mixture after the radiator is installed. If the vehicle shows signs of overheating, check the thermostat, radiator cap, fan operation, and coolant condition at the same time.

Quality Assurance

Denso radiators are built to meet OE manufacturer standards for configuration, durability, and function. Each radiator passes Denso durability and performance testing to support reliable cooling performance under demanding conditions.

This part fits 10 vehicles
Always verify fitment with your vehicle's VIN if unsure. Submodel & trim restrictions may apply.
YearMakeModelBody TypePositionNotes
2007ToyotaSequoia—N/A—
2006ToyotaSequoia—N/A—
2006ToyotaTundraCrew Cab PickupN/A—
2005ToyotaSequoia—N/A—
2005ToyotaTundraCrew Cab PickupN/A—
2004ToyotaSequoia—N/A—
2004ToyotaTundraCrew Cab PickupN/A—
2003ToyotaSequoia—N/A—
2002ToyotaSequoia—N/A—
2001ToyotaSequoia—N/A—
Directly replaces or cross-references 12 part numbers
Cross-reference numbers are provided for identification purposes only. Always confirm fitment before ordering.
APDI — 8012376CSF — 3238DPI Performance Racing Products — 2376OSC — 2376Reach Cooling — 41-2376Spectra Premium — CU2376Toyota — 16400-0F030Toyota — 16400-0F040Toyota — 16401-72090Toyota — 16410-YZZAUTYC Cooling - Archived — 2376Vista Pro — 432441