Denso 221-3125 Radiator
OE Quality 60-Day Returns
Denso

Denso 221-3125 Radiator

Brand Denso 221-3125
Core Height 25.5620
Core Thickness 1.4370
Core Width 23.6250
Inlet Diameter 1.5000
Outlet Diameter 1.5000
Transmission Oil Cooler Included YES
Fits Lexus · 7 vehicles

OE experience. Built to meet rigid OE standards for fit and performance.

Durability tested. Passes strict function and durability checks for dependable cooling.

Transmission oil cooler included. Adds integrated cooling support in one radiator assembly.

Cross-references APDI 8012581, CSF 3150 and CSF 3343 for the same application. See all 12.

$246.81Free shipping
In stock · usually ships same day before 1pm CST
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Order total $246.81
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Free returns within 60 days if it doesn't fit when fitment is verified.
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Denso Radiator for Lexus GX470

The Denso 221-3125 radiator is an OE-style cooling replacement for the 2003-2009 Lexus GX470. Built to match factory specifications for core size, inlet and outlet dimensions, and transmission cooling integration, it supports stable engine temperature control and consistent heat exchange.

  • Fits 2003-2009 Lexus GX470
  • Core height: 25.5620 in.
  • Core width: 23.6250 in.
  • Core thickness: 1.4370 in.
  • Transmission oil cooler included
  • Inlet diameter: 1.5000 in.
  • Outlet diameter: 1.5000 in.

OE-Style Cooling Performance

Denso 221-3125 is engineered from Denso’s OE radiator experience and built to meet original manufacturer standards for configuration, tank design, fin pitch, core dimensions, and materials. For Lexus GX470 cooling system service, this radiator is intended to restore proper heat transfer and maintain reliable operation under demanding driving conditions. The integrated transmission oil cooler helps support both engine and transmission temperature management in one assembly.

This part cross-references Spectra Premium CU2581 for the same application.

Common Reasons to Replace

  • Coolant leaks from a damaged or aging radiator
  • Overheating caused by reduced heat dissipation
  • Transmission temperature concerns tied to radiator cooler failure
  • Restricted flow from internal corrosion or sediment buildup
  • Fitment issues when replacing a worn factory radiator on a Lexus GX470

Installation Notes

Verify inlet and outlet hose sizes, cooler line routing, and mounting points before installation. Flush the cooling system, inspect hoses and clamps, and confirm proper coolant fill and air bleeding after replacement. Because this radiator includes a transmission oil cooler, check all cooler connections for secure sealing during installation.

Quality Assurance

Denso radiators are built to OE standards and undergo durability and function testing before release. The 221-3125 is designed to deliver dependable cooling performance and fitment for the Lexus GX470 platform.

Related reading

This part fits 7 vehicles
Always verify fitment with your vehicle's VIN if unsure. Submodel & trim restrictions may apply.
YearMakeModelPositionNotes
2009LexusGX470N/A—
2008LexusGX470N/A—
2007LexusGX470N/A—
2006LexusGX470N/A—
2005LexusGX470N/A—
2004LexusGX470N/A—
2003LexusGX470N/A—
Directly replaces or cross-references 12 part numbers
Cross-reference numbers are provided for identification purposes only. Always confirm fitment before ordering.
APDI — 8012581CSF — 3150CSF — 3343DPI Performance Racing Products — 2690Lexus — 16400-50310Lexus — 16400-50312Lexus — 16400-50313OSC — 2690Reach Cooling — 41-2581Spectra Premium — CU2581TYC Cooling - Archived — 2690Vista Pro — 433870