Denso 221-3165 Radiator

Brand Denso 221-3165
Core Height 26.5620
Core Thickness 0.8750
Core Width 18.8750
Inlet Diameter 1.5000
Outlet Diameter 1.5000
Transmission Oil Cooler Included YES
Fits Lexus · 3 vehicles

OE experience. Built to meet rigid OE standards for fit, performance, and reliability.

Radiator performance. Helps maintain proper engine cooling and function under demanding conditions.

Transmission oil cooler included. Adds integrated cooling support in one radiator assembly.

Cross-references APDI 8013019, CSF 3298 and CSF 3636 for the same application. See all 11.

$189.65Free shipping
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Denso 221-3165 Radiator for Lexus RX350

The Denso 221-3165 radiator is built for 2007-2009 Lexus RX350 applications and follows OE-style dimensions for proper cooling system fitment. With a 26.5620-inch core height, 18.8750-inch core width, and 0.8750-inch core thickness, it is sized to match the original radiator layout while supporting dependable engine temperature control.

This radiator includes an integrated transmission oil cooler and uses 1.5000-inch inlet and outlet diameters. For Lexus RX350 owners searching for a direct-fit radiator replacement, Denso 221-3165 provides the configuration needed for a clean installation and consistent cooling performance.

Key Features

  • Direct-fit radiator for 2007-2009 Lexus RX350
  • Part number: 221-3165
  • Core dimensions: 26.5620 in. height x 18.8750 in. width x 0.8750 in. thickness
  • Transmission oil cooler included
  • 1.5000-inch inlet and 1.5000-inch outlet diameters
  • OE-style radiator configuration for proper fitment

Detailed Description

Denso radiators are engineered using OE supplier experience and manufacturing standards that focus on fit, function, and durability. The 221-3165 radiator is configured to match the cooling system requirements of the Lexus RX350, helping maintain stable engine temperatures under everyday driving and demanding conditions. Its core size, tank layout, fin pitch, and materials are selected to align with original equipment expectations, making it a practical choice for a Lexus RX350 radiator replacement.

This part cross-references Spectra Premium CU13019 for the same application.

What This Radiator Helps Solve

  • Overheating caused by a worn or leaking radiator
  • Coolant loss from cracked tanks or damaged core sections
  • Poor heat transfer from an aging radiator core
  • Transmission cooling concerns when the factory cooler is part of the system
  • Fitment issues from using the wrong radiator dimensions on a Lexus RX350

Installation Notes and Tips

Verify the inlet and outlet sizes, core dimensions, and transmission cooler layout before installation. Inspect hoses, clamps, and coolant condition during replacement, and confirm the radiator mounts and connections match the vehicle’s original setup. This radiator fits 2007-2009 Lexus RX350, N/A.

Quality Assurance

Denso designs this radiator to meet OE manufacturer standards and subjects it to durability and function testing before release. That process supports reliable cooling-system performance and consistent fitment for the Lexus RX350.

This part fits 3 vehicles
Always verify fitment with your vehicle's VIN if unsure. Submodel & trim restrictions may apply.
YearMakeModelPositionNotes
2009LexusRX350N/A—
2008LexusRX350N/A—
2007LexusRX350N/A—
Directly replaces or cross-references 11 part numbers
Cross-reference numbers are provided for identification purposes only. Always confirm fitment before ordering.
APDI — 8013019CSF — 3298CSF — 3636DPI Performance Racing Products — 13019Lexus — 16041-0P180Lexus — 16041-0P190Lexus — 16041-31480OSC — 13019Reach Cooling — 41-13019Spectra Premium — CU13019TYC Cooling - Archived — 13019