OE Quality
60-Day Returns

Denso 221-3166 Radiator
Overview of the Denso Radiator for Lexus RX300
The Denso 221-3166 radiator is designed specifically for the Lexus RX300, providing reliable cooling performance. This radiator includes a transmission oil cooler, making it a comprehensive solution for your vehicle's cooling system needs.
- Core Height: 17.687 inches
- Core Width: 29.062 inches
- Core Thickness: 0.625 inches
- Inlet Diameter: 1.375 inches
- Outlet Diameter: 1.375 inches
- Includes Transmission Oil Cooler
Detailed Product Specifications
The Denso 221-3166 radiator features a core height of 17.687 inches and a core width of 29.062 inches, providing ample surface area for efficient heat dissipation. With a core thickness of 0.625 inches, this radiator balances durability and cooling capacity. Both the inlet and outlet diameters measure 1.375 inches, ensuring proper coolant flow and compatibility with the Lexus RX300's cooling system. The integrated transmission oil cooler helps maintain optimal transmission temperatures, contributing to overall vehicle performance and longevity.
Compatible Vehicles and Applications
This radiator is compatible with the Lexus RX300 model, engineered to meet the specific cooling requirements of this vehicle. The Denso 221-3166 radiator is suitable for replacing worn or damaged radiators and addressing cooling system issues related to overheating or transmission temperature regulation.
- Overheating engine due to radiator inefficiency
- Transmission overheating caused by lack of oil cooling
- Coolant leaks or damage to the radiator core
- Reduced cooling performance from clogged or corroded radiator
- Maintaining proper engine and transmission operating temperatures
Installation Notes and Tips
When installing the Denso 221-3166 radiator on a Lexus RX300, ensure all connections, including the inlet and outlet hoses, are secure and free of leaks. Properly flush the cooling system before installation to remove debris and contaminants. Verify that the transmission oil cooler lines are correctly connected to maintain transmission cooling functionality. Follow manufacturer torque specifications for mounting hardware to avoid damage.
Quality Assurance and Warranty
Denso radiators are manufactured to meet OEM standards, ensuring reliable fit and function for the Lexus RX300. The 221-3166 radiator undergoes rigorous quality control to provide consistent cooling performance. Warranty coverage details should be confirmed with the supplier or manufacturer, as they may vary by region.
| Brand | Denso |
| Part Number | 221-3166 |
| Core Height | 17.6870 |
| Core Thickness | 0.6250 |
| Core Width | 29.0620 |
| Inlet Diameter | 1.3750 |
| Outlet Diameter | 1.3750 |
| Transmission Oil Cooler Included | YES |
This part fits 3 vehicles. Search below:
| Year | Make | Model | Position | Notes |
|---|---|---|---|---|
| 2003 | Lexus | RX300 | N/A | w/ 16mm Core |
| 2002 | Lexus | RX300 | N/A | w/ 16mm Core |
| 2001 | Lexus | RX300 | N/A | w/ 16mm Core |
* Always verify fitment with your vehicle's VIN if unsure. Submodel & trim restrictions may apply.
This part directly replaces or is cross-referenced with the following part numbers:
Cross-reference numbers are provided for identification purposes only. Always confirm fitment before ordering.