Denso 221-3420 Radiator

Brand Denso 221-3420
Core Height 19.6870
Core Thickness 0.6250
Core Width 27.0620
Inlet Diameter 1.3750
Outlet Diameter 1.3750
Transmission Oil Cooler Included YES
Fits Nissan and INFINITI · 8 vehicles

OE experience. Built with OE-level know-how for reliable fit and performance.

Engine cooling essential. Helps maintain proper cooling and engine function.

Transmission oil cooler included. Adds integrated cooling support in one radiator assembly.

Cross-references APDI 8012459, CSF 2833 and Datsun/Nissan 21460-0W810 for the same application. See all 12.

$168.98Free shipping
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Denso Radiator for Pathfinder and QX4

The Denso 221-3420 radiator is built for direct-fit cooling performance in select Nissan and INFINITI applications. It is engineered to match OE-style dimensions and cooling requirements, with an integrated transmission oil cooler and inlet/outlet sizing that supports proper system flow.

  • Core height: 19.6870 in.
  • Core width: 27.0620 in.
  • Core thickness: 0.6250 in.
  • Transmission oil cooler included: yes
  • Inlet diameter: 1.3750 in.
  • Outlet diameter: 1.3750 in.

OE-Style Cooling Construction

Denso designs radiators to OE manufacturer standards for configuration, tank design, fin pitch, core dimensions, and materials. The 221-3420 follows that approach to support consistent engine temperature control and dependable heat exchange in daily driving and demanding conditions. This radiator is a strong match for 2001-2004 Nissan Pathfinder and 2000-2003 INFINITI QX4 applications, including the 2000 INFINITI QX4 from 01/00. This part cross-references Spectra Premium CU2459 for the same application.

What This Radiator Helps Address

  • Overheating caused by a worn or restricted radiator core
  • Coolant leaks from aging tanks or seams
  • Reduced cooling efficiency from damaged fins or internal blockage
  • Transmission fluid temperature control concerns when the cooler circuit is part of the system
  • Fitment issues from non-OE-style replacement dimensions

Installation Notes and Tips

Verify core dimensions, inlet and outlet size, and transmission cooler connections before installation. Flush the cooling system, inspect hoses and clamps, and confirm the radiator mounts correctly in the vehicle support. For 2001-2004 Nissan Pathfinder and 2001-2003 INFINITI QX4 models, confirm all hose routing and cooler line connections match the original layout before filling and bleeding the system.

Quality Assurance

Denso supplies radiators to OE car makers worldwide, and this radiator is built to the same fitment and durability standards used in OE development. Each unit is tested for durability and function to support reliable cooling performance.

This part fits 8 vehicles
Always verify fitment with your vehicle's VIN if unsure. Submodel & trim restrictions may apply.
YearMakeModelTransmissionPositionNotes
2004NissanPathfinder—N/A—
2003INFINITIQX4—N/A—
2003NissanPathfinder—N/A—
2002INFINITIQX4—N/A—
2002NissanPathfinderAutomaticN/A—
2001INFINITIQX4—N/A—
2001NissanPathfinderAutomaticN/A—
2000INFINITIQX4—N/AFrom 01/00
Directly replaces or cross-references 12 part numbers
Cross-reference numbers are provided for identification purposes only. Always confirm fitment before ordering.
APDI — 8012459CSF — 2833Datsun/Nissan — 21460-0W810Datsun/Nissan — 21460-0W811Datsun/Nissan — 21460-4W007Datsun/Nissan — 21460-4W017DPI Performance Racing Products — 2459OSC — 2459Reach Cooling — 41-2459Spectra Premium — CU2459TYC Cooling - Archived — 2459Vista Pro — 432465