Denso 221-3427 Radiator

Brand Denso 221-3427
Core Height 17.7500
Core Thickness 0.6250
Core Width 29.0000
Inlet Diameter 1.4370
Outlet Diameter 1.4370
Transmission Oil Cooler Included YES
Fits INFINITI · 3 vehicles

OE experience. Built to meet rigid OE standards for fit, performance, and reliability.

Transmission oil cooler included. Integrated cooling helps simplify radiator replacement.

Radiator performance. Essential for proper engine cooling and dependable function.

Cross-references APDI 8012780, CSF 3289 and DPI Performance Racing Products 2780 for the same application. See all 8.

$168.87Free shipping
In stock · usually ships same day before 1pm CST
Step 1 — Confirm fitment
Free return shipping if it doesn't fit when you check fitment here first.
Select your vehicle to confirm fitment
Verify this part fits before purchasing — free returns if it doesn't
Step 2 — Quantity
Order total $168.87
Free shipping to the continental U.S.
Free returns within 60 days if it doesn't fit when fitment is verified.

Denso Radiator for Infiniti M35

The Denso 221-3427 radiator is an OE-style cooling replacement built for 2006-2008 Infiniti M35 applications. It is engineered around factory-style dimensions and materials to support consistent engine temperature control and dependable fitment.

  • Fits 2006-2008 Infiniti M35
  • Core height: 17.7500 in.
  • Core width: 29.0000 in.
  • Core thickness: 0.6250 in.
  • Inlet diameter: 1.4370 in.
  • Outlet diameter: 1.4370 in.
  • Transmission oil cooler included: Yes

OE-Style Cooling Construction

Denso part number 221-3427 is built to match OE radiator configuration standards, including tank design, fin pitch, core dimensions, and material selection. That factory-focused approach helps maintain proper coolant flow and heat transfer in the Infiniti M35 cooling system. This part cross-references Spectra Premium CU2780 for the same application.

What This Radiator Helps Address

  • Overheating caused by a worn or leaking radiator
  • Coolant loss from cracked tanks or damaged core sections
  • Reduced cooling efficiency from age-related internal restriction
  • Transmission fluid temperature control when the factory cooler is used
  • Fitment issues from non-OE-style replacement dimensions

Installation Notes and Tips

Verify inlet and outlet hose sizes, mounting points, and transmission cooler line connections before installation. Flush the cooling system, inspect hoses and clamps, and confirm the radiator cap and coolant condition are serviceable. For 2006-2008 Infiniti M35 applications, compare the original unit to Denso 221-3427 before final assembly to confirm OE-style fitment.

Quality Assurance

Denso supplies radiators to OE vehicle manufacturers worldwide, and this radiator is produced to meet rigid OE standards for performance, reliability, and fitment. Each unit is subjected to durability and function testing to support dependable operation under demanding driving conditions.

This part fits 3 vehicles
Always verify fitment with your vehicle's VIN if unsure. Submodel & trim restrictions may apply.
YearMakeModelPositionNotes
2008INFINITIM35N/A—
2007INFINITIM35N/A—
2006INFINITIM35N/A—
Directly replaces or cross-references 8 part numbers
Cross-reference numbers are provided for identification purposes only. Always confirm fitment before ordering.
APDI — 8012780CSF — 3289DPI Performance Racing Products — 2780Infiniti — 21460-EG200OSC — 2780Reach Cooling — 41-2780Spectra Premium — CU2780TYC Cooling - Archived — 2780