Denso 221-9455 Radiator

Brand Denso 221-9455
Core Height 25.1969
Core Thickness 1.3386
Core Width 18.8976
Inlet Diameter 1.8125
Outlet Diameter 1.0625
Transmission Oil Cooler Included YES
Fits Mercedes-Benz · 32 vehicles

OE experience. Built to OE standards for reliable performance and fit.

Radiator performance. Helps maintain proper engine cooling and function.

Transmission oil cooler included. Adds integrated cooling support in one assembly.

Cross-references APDI 8012907, DPI Performance Racing Products 2875 and Mercedes-Benz 221 500 26 03 for the same application. See all 8.

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Denso Radiator for Mercedes-Benz V8 Cooling

The Denso 221-9455 radiator is built for Mercedes-Benz performance sedans and coupes that demand stable engine temperature control. It combines OE-style fitment with a transmission oil cooler and core dimensions matched to the application for dependable cooling performance.

Key Features

  • Core height: 25.1969 in. for application-specific coverage
  • Core width: 18.8976 in. and core thickness: 1.3386 in.
  • Transmission oil cooler included
  • Inlet diameter: 1.8125 in.; outlet diameter: 1.0625 in.
  • Built to Denso OE standards for configuration, materials, and durability testing
  • Direct replacement radiator for select Mercedes-Benz CL-Class and S-Class models

Detailed Description

Denso part number 221-9455 is a radiator engineered for select Mercedes-Benz applications, including CL65 AMG, S65 AMG, CL63 AMG, S63 AMG, CL550, CL600, S550, and S600 models. It is designed around OE-style radiator configuration details such as tank design, fin pitch, core dimensions, and material selection to support proper engine cooling and heat transfer. For buyers searching for a Mercedes-Benz CL65 AMG radiator or a Mercedes-Benz S600 radiator replacement, this unit provides a direct-fit solution with the correct inlet and outlet sizing and an integrated transmission oil cooler.

Denso’s OE supply experience is reflected in the way this radiator is built and tested. The 221-9455 is intended for vehicles that require consistent cooling under demanding driving conditions, making it a practical choice for restoring factory-style thermal management on compatible Mercedes-Benz CL-Class and S-Class vehicles. This part cross-references Mercedes-Benz 221 500 26 03 and 221 500 31 03 for the same application.

What This Radiator Helps Address

  • Overheating caused by a worn or restricted radiator core
  • Coolant temperature instability during stop-and-go or high-load driving
  • Transmission fluid heat management concerns when the cooler circuit is part of the system
  • Leaks or corrosion in the original radiator assembly
  • Reduced cooling efficiency in aging Mercedes-Benz CL-Class and S-Class vehicles

Installation Notes and Tips

Verify radiator dimensions, inlet and outlet sizes, and transmission cooler connections before installation. Drain coolant fully, inspect hoses and clamps for wear, and confirm the cooling system is flushed before filling with the correct specification coolant. After installation, bleed air from the system and check for leaks at all hose and cooler connections. Fits 2008-2014 Mercedes-Benz CL65 AMG, Primary (Engine Cooling). Fits 2007-2013 Mercedes-Benz S65 AMG, Primary (Engine Cooling). Fits 2008-2010 Mercedes-Benz CL63 AMG. Fits 2008-2010 Mercedes-Benz S63 AMG. Fits 2007-2009 Mercedes-Benz CL550. Fits 2007-2009 Mercedes-Benz CL600, Primary (Engine Cooling). Fits 2007-2009 Mercedes-Benz S550. Fits 2007-2009 Mercedes-Benz S600, Primary (Engine Cooling).

Quality Assurance

Denso radiators are manufactured to OE-level configuration standards and undergo durability and function testing before release. That process supports consistent fitment and reliable cooling performance for Mercedes-Benz applications.

This part fits 32 vehicles
Always verify fitment with your vehicle's VIN if unsure. Submodel & trim restrictions may apply.
YearMakeModelPositionNotes
2014Mercedes-BenzCL65 AMGN/APrimary (Engine Cooling)
2013Mercedes-BenzCL65 AMGN/APrimary (Engine Cooling)
2013Mercedes-BenzS65 AMGN/APrimary (Engine Cooling)
2012Mercedes-BenzCL65 AMGN/APrimary (Engine Cooling)
2012Mercedes-BenzS65 AMGN/APrimary (Engine Cooling)
2011Mercedes-BenzCL65 AMGN/APrimary (Engine Cooling)
2011Mercedes-BenzS65 AMGN/APrimary (Engine Cooling)
2010Mercedes-BenzCL63 AMGN/A—
2010Mercedes-BenzCL65 AMGN/APrimary (Engine Cooling)
2010Mercedes-BenzS63 AMGN/A—
2010Mercedes-BenzS65 AMGN/APrimary (Engine Cooling)
2009Mercedes-BenzCL550N/A—
2009Mercedes-BenzCL600N/APrimary (Engine Cooling)
2009Mercedes-BenzCL63 AMGN/A—
2009Mercedes-BenzCL65 AMGN/APrimary (Engine Cooling)
2009Mercedes-BenzS550N/A—
2009Mercedes-BenzS600N/APrimary (Engine Cooling)
2009Mercedes-BenzS63 AMGN/A—
2009Mercedes-BenzS65 AMGN/APrimary (Engine Cooling)
2008Mercedes-BenzCL550N/A—
2008Mercedes-BenzCL600N/APrimary (Engine Cooling)
2008Mercedes-BenzCL63 AMGN/A—
2008Mercedes-BenzCL65 AMGN/APrimary (Engine Cooling)
2008Mercedes-BenzS550N/A—
2008Mercedes-BenzS600N/APrimary (Engine Cooling)
2008Mercedes-BenzS63 AMGN/A—
2008Mercedes-BenzS65 AMGN/APrimary (Engine Cooling)
2007Mercedes-BenzCL550N/A—
2007Mercedes-BenzCL600N/APrimary (Engine Cooling)
2007Mercedes-BenzS550N/A—
2007Mercedes-BenzS600N/APrimary (Engine Cooling)
2007Mercedes-BenzS65 AMGN/APrimary (Engine Cooling)
Directly replaces or cross-references 8 part numbers
Cross-reference numbers are provided for identification purposes only. Always confirm fitment before ordering.
APDI — 8012907DPI Performance Racing Products — 2875Mercedes-Benz — 221 500 26 03Mercedes-Benz — 221 500 31 03OSC — 2875Reach Cooling — 41-2875Spectra Premium — CU2875TYC Cooling - Archived — 2875