HomeHVAC > Hoses and PipesFour Seasons 65121 A/C Refrigerant Liquid Hose
Part #: 65121

Four Seasons 65121 A/C Refrigerant Liquid Hose

Hose Assembly
⚙️ 46 vehicles fit this part
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📦Hose Assembly
🚗Fitment: Cadillac, Chevrolet, and GMC, Cheyenne, Escalade, Escalade ESV, Sierra 1500, Sierra 1500 Limited, Silverado 1500, Silverado 1500 LD, Silverado 1500 LTD, Tahoe, Yukon, and Yukon XL
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Liquid Line Hose Assembly for R1234YF Systems

Four Seasons 65121 is an A/C refrigerant liquid hose assembly built with aluminum and rubber construction for service in R1234YF systems. It includes the gasket or seal, fittings, and service port, and it is configured as a liquid line hose assembly without a bracket.

Four Seasons Hose Assembly products are part of a focused HVAC line backed by more than 50 years of mobile A/C experience. This Four Seasons 65121 hose assembly is engineered and tested for dependable operation in late-model GM truck and SUV applications.

Key Features

  • Part number: 65121
  • Liquid line hose assembly for R1234YF refrigerant
  • Aluminum / rubber construction
  • P-nut fitting on both ends
  • Gasket or seal included
  • Fittings included
  • Service port included
  • Orifice tube included
  • Without bracket

Application Details

Compatible with late-model Chevrolet, GMC, and Cadillac vehicles that use this liquid line configuration. Fits 2021-2025 Cadillac Escalade ESV, N/A; Fits 2021-2025 Chevrolet Tahoe, N/A; Fits 2021-2025 GMC Yukon, N/A; Fits 2021-2025 GMC Yukon XL, N/A; Fits 2021-2024 Cadillac Escalade, N/A; Fits 2019-2024 Chevrolet Cheyenne, N/A; Fits 2019-2024 Chevrolet Silverado 1500, N/A; Fits 2019-2024 GMC Sierra 1500, N/A; Fits 2022 Chevrolet Silverado 1500 LTD, N/A; Fits 2022 GMC Sierra 1500 Limited, N/A; Fits 2019 GMC Sierra 1500 Limited, N/A; Fits 2019 Chevrolet Silverado 1500 LD, N/A.

This part cross-references UAC HA113926C for the same application.

What This Part Helps Address

  • Refrigerant line leaks at the liquid hose assembly
  • Damaged or worn hose sections in the A/C circuit
  • Failed seals or fittings at hose connection points
  • Service port issues on the liquid line
  • Incorrect hose configuration for R1234YF-equipped vehicles

Installation Notes and Tips

Verify the vehicle’s A/C refrigerant type, hose routing, and connection style before installation. This assembly uses P-nut fittings and includes an orifice tube, so confirm the existing system layout matches the part configuration. Replace any disturbed seals during service and evacuate and recharge the system according to factory procedures.

Quality Assurance

Four Seasons engineers and tests its HVAC components for long service life and trouble-free operation. The brand draws on over 50 years of mobile A/C experience, and part number 65121 is built to meet the demands of modern GM A/C service.

BrandFour Seasons
Part Number65121
PositionHose Assembly
MaterialAluminum / rubber
End 1 TypeP-nut fitting
End 2 TypeP-nut fitting
Refrigerant TypeR1234yf
Gasket Or Seal IncludedIncluded
Fittings IncludedIncluded
Bracket?W/o bracket
DescriptionHose assemblies
Orifice Tube?W/ orifice tube
Service Port IncludedYes
StyleLiquid line hose assembly w/o orifice tube
Switch Port IncludedNo
TypeLiquid line

This part fits 46 vehicles. Search below:

YearMakeModelPositionNotes
2025CadillacEscalade ESVN/Aw/o Orifice Tube; Hose Assembly
2025ChevroletTahoeN/Aw/o Orifice Tube; Hose Assembly
2025GMCYukonN/Aw/o Orifice Tube; Hose Assembly
2025GMCYukon XLN/Aw/o Orifice Tube; Hose Assembly
2024CadillacEscaladeN/Aw/o Orifice Tube; Hose Assembly
2024CadillacEscalade ESVN/Aw/o Orifice Tube; Hose Assembly
2024ChevroletCheyenneN/Aw/o Orifice Tube; Hose Assembly
2024ChevroletSilverado 1500N/Aw/o Orifice Tube; Hose Assembly
2024ChevroletTahoeN/Aw/o Orifice Tube; Hose Assembly
2024GMCSierra 1500N/Aw/o Orifice Tube; Hose Assembly
2024GMCYukonN/Aw/o Orifice Tube; Hose Assembly
2024GMCYukon XLN/Aw/o Orifice Tube; Hose Assembly
2023CadillacEscaladeN/Aw/o Orifice Tube; Hose Assembly
2023CadillacEscalade ESVN/Aw/o Orifice Tube; Hose Assembly
2023ChevroletCheyenneN/Aw/o Orifice Tube; Hose Assembly
2023ChevroletSilverado 1500N/Aw/o Orifice Tube; Hose Assembly
2023ChevroletTahoeN/Aw/o Orifice Tube; Hose Assembly
2023GMCSierra 1500N/Aw/o Orifice Tube; Hose Assembly
2023GMCYukonN/Aw/o Orifice Tube; Hose Assembly
2023GMCYukon XLN/Aw/o Orifice Tube; Hose Assembly
2022CadillacEscaladeN/Aw/o Orifice Tube; Hose Assembly
2022CadillacEscalade ESVN/Aw/o Orifice Tube; Hose Assembly
2022ChevroletCheyenneN/Aw/o Orifice Tube; Hose Assembly
2022ChevroletSilverado 1500N/Aw/o Orifice Tube; Hose Assembly
2022ChevroletSilverado 1500 LTDN/Aw/o Orifice Tube; Hose Assembly
2022ChevroletTahoeN/Aw/o Orifice Tube; Hose Assembly
2022GMCSierra 1500N/Aw/o Orifice Tube; Hose Assembly
2022GMCSierra 1500 LimitedN/Aw/o Orifice Tube; Hose Assembly
2022GMCYukonN/Aw/o Orifice Tube; Hose Assembly
2022GMCYukon XLN/Aw/o Orifice Tube; Hose Assembly
2021CadillacEscaladeN/Aw/o Orifice Tube; Hose Assembly
2021CadillacEscalade ESVN/Aw/o Orifice Tube; Hose Assembly
2021ChevroletCheyenneN/Aw/o Orifice Tube; Hose Assembly
2021ChevroletSilverado 1500N/Aw/o Orifice Tube; Hose Assembly
2021ChevroletTahoeN/Aw/o Orifice Tube; Hose Assembly
2021GMCSierra 1500N/Aw/o Orifice Tube; Hose Assembly
2021GMCYukonN/Aw/o Orifice Tube; Hose Assembly
2021GMCYukon XLN/Aw/o Orifice Tube; Hose Assembly
2020ChevroletCheyenneN/Aw/o Orifice Tube; Hose Assembly
2020ChevroletSilverado 1500N/Aw/o Orifice Tube; Hose Assembly
2020GMCSierra 1500N/Aw/o Orifice Tube; Hose Assembly
2019ChevroletCheyenneN/Aw/o Orifice Tube; Hose Assembly
2019ChevroletSilverado 1500N/Aw/o Orifice Tube; Hose Assembly
2019ChevroletSilverado 1500 LDN/Aw/o Orifice Tube; Hose Assembly
2019GMCSierra 1500N/Aw/o Orifice Tube; Hose Assembly
2019GMCSierra 1500 LimitedN/Aw/o Orifice Tube; Hose Assembly

* Always verify fitment with your vehicle's VIN if unsure. Submodel & trim restrictions may apply.

This part directly replaces or is cross-referenced with the following part numbers:

21242565121844594068510411386593288A66019HA113926C

Cross-reference numbers are provided for identification purposes only. Always confirm fitment before ordering.