OE Quality
60-Day Returns

Gates 51421 Radiator Coolant Hose - Upper
Reliable Radiator Coolant Hose for Mercedes-Benz Vehicles
The Gates Molded Coolant Hose 51421 is engineered to provide dependable cooling system performance for select Mercedes-Benz models. Designed with durable materials and precise dimensions, this radiator coolant hose ensures a secure fit and efficient coolant flow for your C350, E300, E350, and GLK350 vehicles.
- Constructed from EPDM, plastic, and steel for durability and heat resistance
- Molded design with a centerline length of 533 mm (21 inches) for exact fitment
- Features two male quick connectors and two Henn quick connectors for modular hose assembly
- End 1 and End 2 inside diameters both measure 36 mm (1.4 inches) for consistent coolant flow
- Contains no internal spring, ensuring smooth coolant passage without obstruction
About the Gates Molded Coolant Hose Product Line
The Molded Coolant Hose line by Gates focuses on precision-engineered hoses that are molded to exact specifications for specific vehicle applications. This approach enhances fitment accuracy and reduces installation time. The 51421 part benefits from this product line by offering a molded hose with integrated quick connectors, designed to meet the cooling system requirements of Mercedes-Benz models such as the C350, E300, E350, and GLK350.
Detailed Product Description
This radiator coolant hose is made from a combination of EPDM rubber, plastic, and steel components, providing resistance to heat, pressure, and chemical exposure typical in automotive cooling systems. The molded construction ensures a precise shape that matches the original equipment specifications. With a centerline length of 533 mm (21 inches) and consistent inside diameters of 36 mm (1.4 inches) on both ends, the hose maintains optimal coolant flow. The inclusion of two male quick connectors and two Henn quick connectors allows for modular assembly and secure connections without the need for additional clamps or fittings.
Common Applications and Issues Addressed
- Replacement of worn or cracked radiator coolant hoses in Mercedes-Benz C350, E300, E350, and GLK350
- Prevention of coolant leaks caused by hose degradation or improper fit
- Restoration of proper coolant flow to avoid engine overheating
- Elimination of coolant hose failures due to material fatigue or heat damage
- Ensuring secure connections with quick connectors to reduce maintenance time
Installation Notes and Tips
Ensure the cooling system is fully depressurized and cooled before removing the old hose. Verify that the inside diameters and centerline length match the original hose to guarantee proper fitment. The molded design and quick connectors simplify installation, but confirm that all connections are secure to prevent leaks. Avoid twisting or stretching the hose during installation to maintain integrity.
Quality Assurance and Warranty
Gates Molded Coolant Hose 51421 is manufactured to meet or exceed OEM standards for durability and performance. The use of EPDM, plastic, and steel materials ensures resistance to heat and chemical exposure common in automotive cooling systems. While specific warranty details are not provided, Gates products typically come with manufacturer-backed quality assurance to support reliable operation in Mercedes-Benz C350, E300, E350, and GLK350 vehicles.
| Brand | Gates |
| Part Number | 51421 |
| Position | Molded Coolant Hose, Upper |
| Material | Epdm, plastic, steel |
| End 1 Inside Diameter | 1.4 |
| End 1 Inside Diameter | 36 |
| End 2 Inside Diameter | 1.4 |
| End 2 Inside Diameter | 36 |
| Contains Spring | No |
| Centerline Length | 21 |
| Centerline Length | 533 |
| Branch Quantity | 0 |
| 9839 | Yes |
| 9845 | 2 |
| Modular Components | 2 henn quick connectors |
| Modular Components | 2 male quick connectors |
| Modular Hose | Yes |
| Molded | Yes |
| Number of Quick Connect Fittings | 2 |
This part fits 4 vehicles. Search below:
| Year | Make | Model | Liters | Cylinders | Fuel Type | Position | Notes |
|---|---|---|---|---|---|---|---|
| 2010 | Mercedes-Benz | C350 | 3.5L | V6 | GAS | Upper | W/PZEV Emissions; Molded Coolant Hose |
| 2010 | Mercedes-Benz | E350 | 3.5L | V6 | GAS | Upper | Molded Coolant Hose |
| 2010 | Mercedes-Benz | GLK350 | 3.5L | V6 | GAS | Upper | W/PZEV Emissions; Molded Coolant Hose |
| 2008 | Mercedes-Benz | E300 | 3.0L | V6 | GAS | Upper | Molded Coolant Hose |
* Always verify fitment with your vehicle's VIN if unsure. Submodel & trim restrictions may apply.
This part directly replaces or is cross-referenced with the following part numbers:
Cross-reference numbers are provided for identification purposes only. Always confirm fitment before ordering.