Genuine 6421410580 Engine Intake Manifold Gasket

Mercedes-Benz Intake Manifold Gasket

Genuine part number 6421410580 is an engine intake manifold gasket for select Mercedes-Benz diesel applications. It is used to seal the intake manifold to the cylinder head, helping maintain proper intake tract integrity on covered GL350, ML350, E350, S350, R350, Sprinter 2500, Sprinter 3500, E320, GL320, ML320, and R320 models.

Key Features

• Genuine OEM replacement intake manifold gasket
• Fits select Mercedes-Benz GL350, ML350, E350, S350, R350, Sprinter 2500, Sprinter 3500, E320, GL320, ML320, and R320 applications
• Direct-fit sealing component for the intake manifold assembly
• Part number 6421410580 for ordering and verification
• Built for engine sealing service on covered diesel platforms

Detailed Description

This engine intake manifold gasket is a Genuine replacement part identified by part number 6421410580. It is used on 2007-2009 Mercedes-Benz E320, GL320, ML320, and R320; 2010-2015 Mercedes-Benz GL350; 2010-2012 Mercedes-Benz Sprinter 2500 and Sprinter 3500; 2012-2014 Mercedes-Benz ML350; 2012-2013 Mercedes-Benz E350 and S350; and 2012 Mercedes-Benz R350. This part cross-references Mercedes-Benz OE applications for the same engine sealing service.

Common Uses

• Replacing a leaking intake manifold seal
• Restoring intake manifold-to-cylinder head sealing
• Addressing unmetered air entering the intake system
• Correcting intake-related drivability concerns tied to sealing loss
• Servicing the intake system during manifold removal

Installation Notes and Tips

Clean the mating surfaces thoroughly before installation and inspect the intake manifold and cylinder head sealing faces for damage or warpage. Verify the part number 6421410580 against the vehicle VIN and engine configuration before assembly. Follow factory service procedures and torque specifications during reinstallation.

Quality Assurance

Genuine OEM replacement part for select Mercedes-Benz engine applications, including GL350, ML350, and E350 coverage. Use VIN-based verification to confirm exact fitment before purchase.