HomeExhaust > Gaskets and Sealing SystemsGenuine 6421420080 Exhaust Manifold Gasket
Part #: 6421420080

Genuine 6421420080 Exhaust Manifold Gasket

⚙️ 28 vehicles fit this part
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OE Direct Replacement — Bolt-on fit, no modifications needed
🚗Fitment: Mercedes-Benz, Freightliner, and Dodge, E350, GL350, ML350, S350, Sprinter 2500, Sprinter 3500, and R350
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Reliable Exhaust Manifold Gasket for Dodge and Mercedes-Benz

The Genuine 6421420080 exhaust manifold gasket is designed to provide a secure seal for exhaust systems on select Dodge and Mercedes-Benz vehicles. Engineered to maintain proper exhaust flow and prevent leaks, this gasket is compatible with models such as the Dodge E350 and Mercedes-Benz GL350, ML350, R350, S350, Sprinter 2500, and Sprinter 3500.

Key Features of Genuine 6421420080 Exhaust Manifold Gasket

  • Compatible with Dodge E350 and Mercedes-Benz GL350, ML350, R350, S350, Sprinter 2500, and Sprinter 3500
  • Ensures a tight seal between exhaust manifold and cylinder head
  • Durable construction to withstand high temperatures and pressure
  • OEM quality for reliable fit and performance
  • Part number 6421420080 for precise identification and replacement

Detailed Description of the Exhaust Manifold Gasket

This Genuine exhaust manifold gasket (part number 6421420080) is specifically designed to fit a range of Dodge and Mercedes-Benz vehicles, including the Dodge E350 and Mercedes-Benz Sprinter 3500. The gasket creates a critical seal between the exhaust manifold and the engine cylinder head, preventing exhaust gas leaks that can affect engine performance and emissions. Manufactured to meet original equipment specifications, this gasket withstands the extreme heat and pressure generated by the exhaust system, ensuring long-lasting durability and consistent performance.

Common Applications and Issues Addressed

  • Prevents exhaust leaks that cause engine noise and reduced efficiency
  • Eliminates exhaust fumes entering the cabin
  • Maintains proper backpressure for optimal engine operation
  • Helps avoid check engine light triggers related to exhaust leaks
  • Prevents damage to exhaust manifold and cylinder head surfaces

Installation Notes and Tips

  • Ensure mating surfaces are clean and free of old gasket material before installation
  • Use proper torque specifications for manifold bolts to avoid warping
  • Inspect exhaust manifold and cylinder head for cracks or damage prior to gasket replacement
  • Replace gasket promptly if signs of exhaust leaks or damage are present

Quality Assurance and Warranty Information

The Genuine 6421420080 exhaust manifold gasket is manufactured to meet strict OEM standards, ensuring compatibility and durability for Dodge and Mercedes-Benz vehicles. While specific warranty terms may vary, Genuine parts typically come with a limited warranty covering defects in material and workmanship. Refer to the vehicle manufacturer or parts provider for detailed warranty information.

This part fits 28 vehicles. Search below:

YearMakeModelFuel TypePositionNotes
2013Mercedes-BenzE350DIESELN/AManifold to Crank Case
2013Mercedes-BenzGL350N/AManifold to Crank Case
2013Mercedes-BenzML350DIESELN/AManifold to Crank Case
2013Mercedes-BenzS350N/AManifold to Crank Case
2012Mercedes-BenzE350DIESELN/AManifold to Crank Case
2012Mercedes-BenzGL350N/AManifold to Crank Case
2012Mercedes-BenzML350DIESELN/AManifold to Crank Case
2012Mercedes-BenzR350DIESELN/AManifold to Crank Case
2012Mercedes-BenzS350N/AManifold to Crank Case
2012Mercedes-BenzSprinter 2500N/AManifold to Crank Case
2012Mercedes-BenzSprinter 3500N/AManifold to Crank Case
2011Mercedes-BenzE350DIESELN/AManifold to Crank Case
2011Mercedes-BenzGL350N/AManifold to Crank Case
2011Mercedes-BenzML350DIESELN/AManifold to Crank Case
2011Mercedes-BenzR350DIESELN/AManifold to Crank Case
2011Mercedes-BenzSprinter 2500N/AManifold to Crank Case
2011Mercedes-BenzSprinter 3500N/AManifold to Crank Case
2010Mercedes-BenzGL350N/AManifold to Crank Case
2010Mercedes-BenzML350DIESELN/AManifold to Crank Case
2010Mercedes-BenzR350DIESELN/AManifold to Crank Case
2010Mercedes-BenzSprinter 2500N/AManifold to Crank Case
2010Mercedes-BenzSprinter 3500N/AManifold to Crank Case
2009DodgeSprinter 2500N/AManifold to Crank Case
2009DodgeSprinter 3500N/AManifold to Crank Case
2008DodgeSprinter 2500N/AManifold to Crank Case
2008DodgeSprinter 3500N/AManifold to Crank Case
2007DodgeSprinter 2500N/AManifold to Crank Case
2007DodgeSprinter 3500N/AManifold to Crank Case

* Always verify fitment with your vehicle's VIN if unsure. Submodel & trim restrictions may apply.

This part directly replaces or is cross-referenced with the following part numbers:

Cross-reference numbers are provided for identification purposes only. Always confirm fitment before ordering.