What breaks most · 2001 to 2015 model years

Mercedes-Benz ML350 problems by year

Owners have filed 697 safety complaints with NHTSA about the Mercedes-Benz ML350 across model years 2001 to 2015. One year stands out: 2006 for powertrain and transmission complaints. The quietest years are 2001, 2005 and 2003.

  • Years to check closely: 2006
  • Fewest complaints: 2001, 2005, 2003
Complaints on file
6972001 to 2015, all trims
Worst year
2006139 complaints
Crashes reported
4265 fires · 42 injuries · 0 deaths
Typical failure mileage
60kMedian where owners gave mileage
Recall campaigns
33Across the years shown

Complaints by model year

Raw filings with NHTSA, not adjusted for how many were sold.

Complaints filed per model year. Select a bar to load that year below.
Complaints, crashes and recalls per Mercedes-Benz ML350 model year
Model yearComplaintsCrashesRecallsMost-reported component
100 Child Seat (1)
2400 Steering (11)
3130 Steering (6)
2100 Steering (5)
13962 Powertrain and transmission (39)
7062 Seats (27)
5842 Steering (22)
7413 Air bags (40)
9123 Air bags (62)
7953 Air bags (54)
3534 Engine (13)
2515 Engine (6)
2844 Unknown or other (9)
2175 Brakes (5)

What fails on the 2006 Mercedes-Benz ML350

Components named in 2006 Mercedes-Benz ML350 complaints, with links to matching parts
ComponentShare of complaintsFilingsCrashesParts for this job
Powertrain and transmissionTransmission parts 39 2 Shop all powertrain and transmission parts, not filtered to this vehicle
EngineEngine gaskets and seals 26 1 Shop engine parts for the 2006 Mercedes-Benz ML350
Electrical systemAlternators, starters and ignition 22 1 Shop electrical system parts for the 2006 Mercedes-Benz ML350
Engine and coolingRadiators, thermostats and cooling 17 1 Shop engine and cooling parts for the 2006 Mercedes-Benz ML350
Seats 14 0 —
SteeringPower steering pumps, racks and hoses 10 1 Shop steering parts for the 2006 Mercedes-Benz ML350
Exterior lightingHeadlights, tail lights and bulbs 7 0 Shop exterior lighting parts for the 2006 Mercedes-Benz ML350
Speed control and throttleThrottle and pedal sensors 6 2 Shop speed control and throttle parts for the 2006 Mercedes-Benz ML350

One complaint can name more than one component, so shares add to more than 100%. "Unknown or other" is NHTSA's uncategorized bucket and is shown but never ranked.

In owners' words

Complaint narratives as filed with NHTSA, trimmed for length.

  • 2006 · Powertrain and transmission96710 mi

    Vehicle was making a roaring noise, rear differential was gone and had to be replaced. Front differential is also bad and will have to be replaced in the near future.

How to read this page

Every figure comes from the National Highway Traffic Safety Administration's public complaint database, which holds every safety-related defect complaint filed by owners since 1995. We refresh it monthly and count each complaint once per component it names. Data through September 30, 2026.

NHTSA only accepts safety-related complaints. Rattles, paint, infotainment bugs and other annoyances are under-reported here, so this page is a map of what fails in ways owners consider dangerous, not a full reliability score.

Counts are raw. Use the year-over-year shape and the component mix, not the absolute numbers. Where a component maps to parts we stock, the row links to that category filtered to the year you are viewing. Air bag and seat belt complaints link to the recall checker instead, because those repairs are almost always covered.

Common questions

Which Mercedes-Benz ML350 years have the most problems?

By NHTSA complaint volume, 2006 carries the most filings on the Mercedes-Benz ML350. The 2006 alone has 139 complaints, led by powertrain and transmission.

What is the most common Mercedes-Benz ML350 problem?

On the 2006 model year, the most-reported component is powertrain and transmission with 39 complaints. The table above lists the top components for every year.

At what mileage do Mercedes-Benz ML350 problems start?

The median mileage at failure across all Mercedes-Benz ML350 complaints that include mileage is about 60,000 miles. Older model years skew higher; the per-year figure is in the "at a glance" card.

Are these complaints verified?

No. NHTSA publishes complaints as submitted and does not investigate individual filings. Patterns across hundreds of complaints are meaningful; a single one is not.

Other Mercedes-Benz models

Source: NHTSA Office of Defects Investigation complaint and recall files, data through 2026-09-30. Complaint text is published by NHTSA as filed by owners. PartCatalog does not verify individual complaints and this page is not a safety rating.